Removes genes having a sum of counts accross all samples lesser than the specified threshold. It returns un aupdated TCC object, which count element contains the filtered expression matrix.
filter_low_counts(tcc, thr)data to be filtered to remove low count genes
the sum of counts across all samples to be exceeded for a gene
a TCC-Class object
data("abiotic_stresses")
tcc_object <- DIANE::normalize(abiotic_stresses$raw_counts,
abiotic_stresses$conditions, iteration = FALSE)
threshold = 10*length(abiotic_stresses$conditions)
tcc_object <- DIANE::filter_low_counts(tcc_object, threshold)
normalized_counts <- TCC::getNormalizedData(tcc_object)